Can You Run Gemma 4 on an RTX 5080 (16GB VRAM)?
Yes — best fit is Gemma 4 12B at Q4_0 (4-bit) (~6.7GB) ✅ Comfortable, using 15GB of usable memory on a 16GB RTX 5080.
Every Gemma 4 model on this configuration
| Model | Best quant | Size | Status |
|---|---|---|---|
| Gemma 4 E2B | BF16 (16-bit) | ~8 GB | ✅ Comfortable |
| Gemma 4 E4B | SFP8 (8-bit) | ~7.5 GB | ✅ Comfortable |
| Gemma 4 12B | Q4_0 (4-bit) | ~6.7 GB | ✅ Comfortable |
| Gemma 4 26B A4B | — | — | ❌ Won't fit |
| Gemma 4 31B | — | — | ❌ Won't fit |
How we got this verdict
16 - 1 = 15GB usable VRAM (the driver and OS reserve roughly 1 GB).
12B lands on Q4_0 here, so grab the official QAT (quantization-aware training) checkpoint instead of a generic Q4_0 quant. Google shipped a full-quality QAT build for 12B at essentially the same ~7.2GB download size, with noticeably better output quality than a naive 4-bit quant. See the QAT guide for exact file names.
Switching to the RTX 3090 (24GB VRAM) unlocks 31B at Q4_0 (4-bit) — a step up from 12B here.
The fastest lever on a fixed budget isn't more VRAM on the same card — it's switching cards. Compare this tier against neighboring cards below, or check the full checker for any GPU model.
Try a different configuration
Best fit: Gemma 4 12B · Q4_0 (4-bit) · ~6.7 GB ✅ Comfortable
FAQ
Can a RTX 5080 (16GB VRAM) run the 31B flagship model?
No — the 31B model needs at least 17.4GB usable memory even at Q4_0, and this configuration only has 15GB usable. Gemma 4 12B is the largest model that fits here.
What's the best Gemma 4 model for a RTX 5080 (16GB VRAM)?
Gemma 4 12B at Q4_0 (4-bit) (~6.7GB) is the best fit — it's the largest model that runs comfortably within the 15GB of usable memory here.
What if I have more or less memory than 16GB VRAM?
With more (e.g. RTX 3090), you can run larger models or the same model more comfortably — see the RTX 3090 page. With less (e.g. RTX 4080), the best-fitting model gets smaller or tighter — see the RTX 4080 page.
Related
Gemma 4 on RTX 3070/3080
The full setup guide for this device family.
Can You Run Gemma 4 on an RTX 4080 (16GB VRAM)?
NVIDIA GPU — 16GB VRAM
Can You Run Gemma 4 on an RTX 3090 (24GB VRAM)?
NVIDIA GPU — 24GB VRAM
Gemma 4 Hardware Requirements
The full memory table this checker is built on.
Full Hardware Checker
Every device type, every model, one tool.